Beyond ion flux: the potassium channel KV1.3 and its regulatory function in neutrophils
John Ku , Hans-Joachim Anders , Markus Sperandio and Roland Immler
2026 Current Opinion in Immunology
Publications
Posttranslational sialylation and its impact on neutrophil recruitment
Nussbaumer K, Marth JD, Sperandio M.
2025 Journal of Leukocyte Biology
Neonatal neutrophils exhibit reduced NLRP3 inflammasome activation
Lou Martha Wackerbarth, Sonja Birke Seifert, Matteo Napoli, Ina Rohwedder, Thomas Vogl, Christoph Scheiermann, Thomas Kolben, Claudia Nussbaum, Monika Pruenster, Roland Immler, Markus Sperandio
2025 Journal of Leukocyte Biology
Maternal rhythms suppress neonatal inflammation
2024 Nature Metabolism
E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation
Monika Pruenster, Roland Immler, Jonas Roth, Tim Kuchler, Thomas Bromberger, Matteo Napoli, Katrin Nussbaumer, Ina Rohwedder, Lou Martha Wackerbarth, Chiara Piantoni, Konstantin Hennis, Diana Fink, Sebastian Kallabis, Tobias Schroll, Sergi Masgrau-Alsina, Agnes Budke, Wang Liu, Dietmar Vestweber, Christian Wahl-Schott, Johannes Roth, Felix Meissner, Markus Moser, Thomas Vogl, Veit Hornung, Petr Broz & Markus Sperandio
2023 Nature Immunology
A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny
Rohwedder I, Wackerbarth LM, Heinig K, Ballweg A, Altstätter J, Ripphahn M, Nussbaum C, Salvermoser M, Bierschenk S, Straub T, Gunzer M, Schmidt-Supprian M, Kolben T, Schulz C, Ma A, Walzog B, Heinig M, Sperandio M.
2023 JCI Insight
Events
***SPECIAL EVENT*** PILOT International Symposium on Perinatal and Early Life Immunity
PILOT will be hosting an International Symposium on Perinatal and Early Life Immunity from 9-12 April 2025 at the Historisches Kaufhaus in Freiburg
We already have a fantastic line-up of invited speakers for this event. We plan to complement this with talks selected on the basis of abstracts and there will also be opportunities to present posters.
More details will be posted here as they are finalized; in the meantime, please save the date!